Major women's health study supports hormone replacement therapy in early menopause – Medical Xpress
Click here to sign in with or
Forget Password?
Learn more
share this!
31
Twit
Share
Electronic mail
Might 4, 2024
This text has been reviewed based on Science X’s editorial process and policies. Editors have highlighted the next attributes whereas making certain the content material’s credibility:
fact-checked
peer-reviewed publication
respected information company
proofread
by Dennis Thompson
Hormone substitute remedy can safely ease middle-aged ladies’s signs throughout early menopause, knowledge from a serious ladies’s well being research present.
Ladies youthful than 60 can use hormone substitute to deal with signs like scorching flashes and evening sweats with out considerably rising their danger of breast cancer or different well being issues, based on long-term outcomes from the Ladies’s Well being Initiative (WHI).
“The WHI findings ought to by no means be used as a motive to disclaim hormone remedy to ladies in early menopause with bothersome menopausal signs,” mentioned lead researcher Dr. JoAnn Manson, chief of preventive drugs at Brigham and Ladies’s Hospital in Boston.
“Many ladies are good candidates for therapy and, in shared decision-making with their clinicians, ought to be capable of obtain acceptable and personalised well being care for his or her wants,” Manson added in a hospital information launch.
The WHI concerned greater than 160,000 postmenopausal women ages 50 to 79. The research tracked their charges of coronary heart illness, most cancers and hip fractures, and in addition included randomized clinical trials of greater than 68,000 ladies to check potential growing older therapies like hormone remedy or calcium and vitamin D supplementation.
Previous to the WHI, research had reported that older ladies who took hormone remedy had decrease dangers of coronary heart illness, stroke, dementia, continual illness and dying, researchers mentioned in background notes.
A WHI medical trial slammed the brakes on hormone replacement therapy in 2002, nonetheless, reporting that ladies taking mixture (estrogen and progestin) hormone remedy had an elevated danger for breast most cancers, coronary heart illness, stroke and blood clots.
However as ladies collaborating within the WHI have been adopted over two extra many years, a extra nuanced image of hormone remedy’s dangers and advantages has emerged.
Findings proceed to point out that hormone remedy does nothing to lower ladies’s danger for well being issues associated to growing older like coronary heart illness or hip fractures, counter to pre-WHI research.
Nonetheless, hormone remedy has been proven to not be as dangerous for middle-aged ladies nearing menopause, and useful in coping with signs associated to that change in life.
“Ladies even have extra choices for therapy now, together with estrogen in decrease doses and delivered via the pores and skin as a patch or gel, which can additional scale back dangers,” Manson mentioned. “Non-hormonal therapies are additionally out there.”
This WHI replace, which was revealed Might 1 within the Journal of the American Medical Affiliation, additionally contains recent info on the worth of low-fat diets and calcium and vitamin D supplementation.
Though calcium and vitamin D dietary supplements do not scale back danger of hip fracture in growing older ladies, researchers famous that these dietary supplements might help fill nutrient gaps amongst these not consuming a balanced weight-reduction plan.
In the meantime, low-fat diets now are related to a lowered danger of dying from breast cancer, researchers report. Earlier WHI findings had discovered that low-fat diets didn’t scale back danger of breast or colorectal most cancers.
Researchers suggest that ladies discuss with their docs about whether or not a low-fat weight-reduction plan weight-reduction plan or calcium and vitamin D dietary supplements can be good for them.
Extra info: JoAnn E. Manson et al, The Ladies’s Well being Initiative Randomized Trials and Medical Follow, JAMA (2024). DOI: 10.1001/jama.2024.6542
Copyright © 2024 HealthDay. All rights reserved.
Copyright © 2024 HealthDay. All rights reserved.
Discover additional
Fb
Twitter
Electronic mail
Suggestions to editors
Might 1, 2024
0
Apr 30, 2024
0
Apr 30, 2024
0
Apr 29, 2024
1
Apr 23, 2024
1
Might 4, 2024
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 1, 2024
Apr 10, 2024
Feb 23, 2023
Might 15, 2023
Might 17, 2017
Jan 19, 2023
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 3, 2024
Might 2, 2024
Might 2, 2024
Use this manner if in case you have come throughout a typo, inaccuracy or want to ship an edit request for the content material on this web page. For normal inquiries, please use our contact form. For normal suggestions, use the general public feedback part under (please adhere to guidelines).
Please choose essentially the most acceptable class to facilitate processing of your request
Thanks for taking time to supply your suggestions to the editors.
Your suggestions is essential to us. Nonetheless, we don’t assure particular person replies because of the excessive quantity of messages.
Your e mail handle is used solely to let the recipient know who despatched the e-mail. Neither your handle nor the recipient’s handle can be used for some other objective. The data you enter will seem in your e-mail message and isn’t retained by Medical Xpress in any kind.
Get weekly and/or day by day updates delivered to your inbox. You may unsubscribe at any time and we’ll by no means share your particulars to 3rd events.
More information Privacy policy
We maintain our content material out there to everybody. Take into account supporting Science X’s mission by getting a premium account.
Each day science information on analysis developments and the most recent scientific improvements
The newest engineering, electronics and expertise advances
Probably the most complete sci-tech information protection on the net
