In a study published in the US National Library of Medicine National Institutes of Health, statins causing myositis and myalgia was analysed.
The study noted: “The best recognised and most commonly reported AEs of statins include muscle pain, fatigue and weakness as well as rhabdomyolysis.
“While individual randomised controlled trials (RCTs) often fail to show an excess of muscle problems or symptoms, meta-analysis of randomised double-blind, placebo-controlled trials have shown increased myositis in patients receiving statins relative to, with myositis there defined as creatinine kinase (CK) which is 10 times the upper limit of normal with myalgia.
“An overall null effect of statins on muscle pain in clinical trials may therefore indicate that, in the samples selected for these trials, statins caused muscle pain in approximately as many people as they relieved it.
“In support of this view, triangulating evidence suggest that statins have a causal role in myalgia as well as muscle weakness in some people.”
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